Command Line Interface

Drug2Ways Command Line Interface

drug2ways

drug2ways

drug2ways [OPTIONS] COMMAND [ARGS]...

combine

Run drug2ways for a given network and get sources that optimize given targets.

drug2ways combine [OPTIONS]

Options

-l, --log

Activate debug mode

-o, --output <output>

Output directory

-c, --combination-length <combination_length>

Required Combination length. Number of drugs in each combination.

-a, --activation-threshold <activation_threshold>

Activation threshold

--simple

Count only simple paths, i.e. paths without cycles.

-l, --lmax <lmax>

Required Maximum length of paths

-t, --targets <targets>

Path to file with source nodes

-s, --sources <sources>

Path to file with source nodes

-f, --fmt <fmt>

Graph fmt

Options

csv | tsv | graphml | bel | json | pickle

-g, --graph <graph>

Required Path to the network

explore

Run drug2ways for a given network.

drug2ways explore [OPTIONS]

Options

-t, --time

Export time measurements

-l, --log

Activate debug mode

-d, --drug-search-bel

Drug search for BEL graphs

-n, --name <name>

Name for output file

-o, --output <output>

Output directory

--simple

Count only simple paths, i.e. paths without cycles.

-l, --lmax <lmax>

Required Maximum length of paths

-t, --targets <targets>

Path to file with source nodes

-s, --sources <sources>

Path to file with source nodes

-f, --fmt <fmt>

Graph fmt

Options

csv | tsv | graphml | bel | json | pickle

-g, --graph <graph>

Required Path to the network

optimize

Run drug2ways for a given network and get sources that optimize given targets.

drug2ways optimize [OPTIONS]

Options

-l, --log

Activate debug mode

-o, --output <output>

Output directory

-a, --activation-threshold <activation_threshold>

Activation threshold

--simple

Count only simple paths, i.e. paths without cycles.

-l, --lmax <lmax>

Required Maximum length of paths

-t, --targets <targets>

Path to file with source nodes

-s, --sources <sources>

Path to file with source nodes

-f, --fmt <fmt>

Graph fmt

Options

csv | tsv | graphml | bel | json | pickle

-g, --graph <graph>

Required Path to the network

pathway-analysis

Run drug2ways pathway enrichment on the paths.

drug2ways pathway-analysis [OPTIONS]

Options

-l, --log

Activate debug mode

-o, --output <output>

Output directory

--simple

Count only simple paths, i.e. paths without cycles.

-l, --lmax <lmax>

Required Maximum length of paths

-t, --targets <targets>

Path to file with source nodes

-s, --sources <sources>

Path to file with source nodes

-f, --fmt <fmt>

Graph fmt

Options

csv | tsv | graphml | bel | json | pickle

-g, --graph <graph>

Required Path to the network

validate-with-data

Run validation with RCR for a given network and experimental data.

drug2ways validate-with-data [OPTIONS]

Options

-l, --log

Activate debug mode

-n, --name <name>

Name for output file

-o, --output <output>

Output directory

--simple

Count only simple paths, i.e. paths without cycles.

-l, --lmax <lmax>

Required Maximum length of paths

-t, --target <target>

Name of the drug to be used as target

-t, --target <target>

Name of the drug to be used as source

-f, --fmt <fmt>

Graph fmt

Options

csv | tsv | graphml | bel | json | pickle

-g, --graph <graph>

Required Path to the network